The globalization of public health poses new threats to health but als
o holds important opportunities in the coming century. This commentary
identifies the major threats and opportunities presented by the proce
ss of globalization and emphasizes the need for transnational public h
ealth approaches to take advantage of the positive aspects of global c
hange and to minimize the negative ones. Transnational public health i
ssues are areas of mutual concern for the foreign policies of all coun
tries. These trends indicate a need for cross-national comparisons (e.
g., in the areas of health financing and policy development) and for t
he development of a transnational research agenda in public health.