Ba. Feltis et al., ACUTE ACALCULOUS CHOLECYSTITIS (AAC) RESULTING IN GALLBLADDER PERFORATION IN A SOLID-ORGAN TRANSPLANT RECIPIENT - A CASE-REPORT, Clinical transplantation, 12(3), 1998, pp. 278-280
Gallbladder perforation is a frequent complication of acute acalculous
cholecystitis (AAC), resulting in substantially increased morbidity a
nd mortality. Two groups of patients are at increased risk for perfora
tion: those with systemic diseases (especially peripheral vascular dis
ease, intrinsic heart disease, or diabetes) and those who are chronica
lly immunosuppressed. The current population of solid organ transplant
recipients meets both criteria. We describe an unusual case of gallbl
adder perforation as a complication of AAC in an otherwise healthy kid
ney transplant recipient. Because transplant recipients are at increas
ed risk for gallbladder perforation, maintaining a high index of suspi
cion for this complication will help avoid the increased morbidity and
mortality associated with this diagnosis.