The manifestations of multiple myeloma are protean and related to bony
osteolytic lesions, and to medullar and renal insufficiency. We repor
t a patient who presented with otalgia as the inaugural symptom of mul
tiple myeloma. Local irradiation combined with systemic chemotherapy l
ed to the disappearance of the temporal bone mass and the accompanying
symptoms. To date, 24 months after the diagnosis, the patient is stil
l in remission. The literature on otological involvement in multiple m
yeloma is reviewed. Symptoms are non-specific and include hearing loss
, tinnitus, dizziness, facial paralysis, and otalgia. The diagnosis of
multiple myeloma should be considered in the presence of a temporal b
one mass.