M. Takemori et al., OVARIAN MIXED GERM-CELL TUMOR COMPOSED OF POLYEMBRYOMA AND IMMATURE TERATOMA, Gynecologic oncology (Print), 69(3), 1998, pp. 260-263
We report the case of a 41-year-old woman with ovarian mixed germ cell
tumor which was composed of polyembryoma and immature teratoma and wh
o had high serum levels of alpha-fetoprotein (AFP) and human chorionic
gonadotropin (hCG). By immunohistochemical methods, AFP was found in
yolk sac cells of the embryoid bodies and immature hepatoid tissues, a
nd hCG was found in giant syncytiotrophoblastic cells. She was treated
with surgery followed by cisplatin-based combination chemotherapy. Sh
e is well, and her serum levels of AFP and hCG have not been elevated
for more than 4 years after the treatment. (C) 1998 Academic Press.