Bb. Beard et al., A SYSTEM FOR POSTOPERATIVE VISUALIZATION AND ANALYSIS OF LEFT-VENTRICULAR PRESSURE-VOLUME LOOPS, Computers in biology and medicine, 28(1), 1998, pp. 1-12
A patient monitoring system for continuous real-time monitoring of lef
t ventricular (LV) function in the postoperative setting was developed
. Common hemodynamic parameters and LV functional indices are all calc
ulated from left ventricular pressure-volume loops (PV-loops). Visuali
zation of the PV-loops, along with the hemodynamic parameter derived f
rom them, provides valuable insight into ventricular function and pati
ent recovery. The pressure component is obtained via a pressure sensin
g catheter placed during surgery. Volume is measured via non-imaging r
adionuclide techniques using a modified Capintec-VEST. Following surge
ry and transfer to the recovery unit, the patient's blood is labeled w
ith Tc-99m. A portable gamma camera is used to measure baseline ejecti
on fraction (EF) and to aid in placing the VEST. The specific radioact
ivity of the blood is calibrated using the baseline EF and thermodilut
ion cardiac output. To confirm the volume measurement accuracy of this
technique six patients undergoing bilateral heart catheterization wer
e studied. Single-plane cineventriculographic LV volumes were compared
to those calculated from the VEST's time activity curve. (C) 1998 Els
evier Science Ltd. All rights reserved.