Introduction of influenza viruses with gene segments of avian origin i
nto the human population may result in the emergence of Mew pathogenic
human influenza viruses. The recent infection of a 3-year-old boy wit
h an influenza A (H5N1) virus of avian origin can be considered as an
example of such an event. However; this virus, influenza A/Hong Kong/1
56/97 (H5N1) and the 17 additional H5N1 viruses isolated from humans h
y the end of 1997 lack the ability to spread efficiently amongst human
s and therefore have limited pandemic potential. However; the possibil
ity of reassortment of these viruses with currently circulating human
viruses illustrates the need for pandemic preparedness. (C) 1998 Elsev
ier Science Ltd. All rights reserved.