Background. ''Silent'' aspiration was recognized to be a more frequent
complication at this hospital in patients who have had coronary arter
y bypass grafting than in the general surgical population. Methods. A
case-control retrospective study covering a 4.5-year period was conduc
ted to determine risk factors for pharyngeal dysfunction resulting in
silent aspiration. Results. Significant predictors of silent aspiratio
n were age, history of cerebral vascular disease, insulin-dependent di
abetes mellitus, myocardial infarction, and chronic obstructive pulmon
ary disease. Intraaortic balloon pump and number of units of fresh-fro
zen plasma were the only independent intraoperative factors associated
with silent aspiration in a model using continuous variables directly
. Cold fibrillation was used in 7 of 53 study cases but no control pat
ients, so it could not be modeled. Postoperative complications occurri
ng with greater frequency included neurologic complications, adverse p
ulmonary outcomes, repeat surgical interventions, infection, and death
. Using an Aspiration Risk Profile developed from the retrospective st
udy, in a detailed prospective study of 10 patients, 3 of 4 patients w
ith postoperative dysphagia had objective evidence of stroke. Conclusi
ons. These findings suggest that postoperative coronary artery bypass
graft dysphagia may be the result of intraoperative cerebral injury, a
nd that careful postoperative clinical evaluation of coronary artery b
ypass graft patients with risk factors may result in early diagnosis o
f pharyngeal dysfunction with the goals of preventing silent aspiratio
n and reducing morbidity, mortality, and hospital cost. (C) 1998 by Th
e Society of Thoracic Surgeons.