Vl. Caja et al., THE EFFECT OF BEAD DIAMETER ON THE ACCURACY OF 2 CURRENT TECHNIQUES USED TO QUANTIFY BONE INGROWTH IN POROUS-COATED IMPLANTS, Journal of materials science. Materials in medicine, 5(1), 1994, pp. 29-32
The effect of the bead diameter on the accuracy of two techniques used
in bone ingrowth quantification, microradiography and backscattered e
lectron imaging-scanning electron microscopy (BEI-SEM), was assessed u
sing porous-coated implants. Two groups of seven titanium porous impla
nts (group A: bead size 250-350 mum and group B: 500-700 mum) were imp
lanted for 12 weeks in a canine model. After euthanasia, the same hist
ological slides were prepared for microradiography and BEI-SEM. The pe
rcentage of bone, bone ingrowth, bone ongrowth, porosity and bone inde
x were determined by a point counting method using images from both te
chniques. ANOVA and Tukey's test were used to compare the results from
the different bead sizes and techniques. The results showed significa
nt higher bone ingrowth in microradiography groups, and significant lo
wer porosity in only the fine-bead microradiography group (group A siz
e). Microradiography also obtained significantly higher bone ongrowth,
but only for the coarse bead size group (group B). From these results
it was concluded that microradiography decreases the porosity of the
porous coating compared with BEI-SEM. This effect seems to be dependen
t on the bead diameter. The smaller the diameter, the greater the effe
ct. Furthermore, microradiography increases bone ingrowth which seems
to be affected independently of the bead diameter, becoming the most s
ensitive parameter to increase.