J. Muhonen et al., EFFECT OF POLYGLYCOLIC ACID MEMBRANE ON BONE REGENERATION AROUND TITANIUM IMPLANTS INSERTED IN BONE SOCKETS, Journal of materials science. Materials in medicine, 5(1), 1994, pp. 40-42
An experimental animal model was used to evaluate the value of resorba
ble, non-permeable polyglycolic acid (PGA) membranes in relation to fi
xtures implanted into simulated extraction sockets. Branemark fixtures
(length 7.0 mm, diameter 3.75 mm) were implanted into edentulous area
s of maxillary bone in six sheep. Five fixtures were covered with 0.15
-mm-thick PGA membrane (Biofix(R)) held in place with a cover screw (P
GA group) and five were implanted without membrane (control group). Th
e animals were killed after 4 months and undecalcified mesiodistal sec
tions were prepared from resected jaw specimens. Histomorphometry was
used to measure the distance from the shoulder of the fixture to the l
evel of intimate bone contact (SB distance). SB distance was found to
be greater in the PGA than in the control group in relation both to th
e mesial (1.44 +/- 0.88 mm versus 0.96 +/- 0.47 mm) and distal (1.13 /- 0.80 mm versus 0.77 +/- 0.63 mm) aspects of implants. This statisti
cally not significant difference in bone regeneration between the two
groups is related to the physical properties of the PGA membrane used.