THE TOTAL SYNTHESIS OF TRITIATED AND DEUTERATED 5-PXO-ETE, A NOVEL INFLAMMATORY MEDIATOR

Authors
KHANAPURE SP SHI XX POWELL WS ROKACH J
Citation
Sp. Khanapure et al., THE TOTAL SYNTHESIS OF TRITIATED AND DEUTERATED 5-PXO-ETE, A NOVEL INFLAMMATORY MEDIATOR, Journal of organic chemistry, 63(12), 1998, pp. 4098-4102
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
63
Issue
12
Year of publication
1998
Pages
4098 - 4102
Database
ISI
SICI code
0022-3263(1998)63:12<4098:TTSOTA>2.0.ZU;2-J
Abstract
The total synthesis of 11,12,14,15-tetratritiated and deuterated 5-oxo -ETE is accomplished using a novel bisacetylene precursor 14. The synt heses of these labeled derivatives are necessary in order to investiga te further the role and biochemistry of the novel inflammatory mediato r and eosinophilic chemotactic agent 5-oxo-ETE.