Hypnic headache syndrome is a rare benign disorder which occurs in the
elderly. It presents as a holocephalic or, less frequently, hemicrani
al headache during night sleep, lasting between 20 and 180 min; it is
not associated with autonomic signs and responds well to lithium carbo
nate. We report a new case which responded well to indomethacin, and s
uggest that indomethacin may be used as an alternative treatment in th
is rare headache syndrome of the elderly.