In horses, the urethra is nor a site that commonly requires surgical t
reatment. Occasionally, surgery is indicated to resolve disease of the
urethra, and some urinary tract disorders may require surgical manipu
lation of the urethra.This article discusses the major indications for
urethral surgery in male and female horses. The urethral process in m
ale horses can be affected with locally invasive disease, such as squa
mous cell carcinoma or cutaneous habronemiasis. These disorders may re
quire amputation of the urethral process. Surgery of the penile urethr
a is indicated to treat urolithiasis; depending on the location of the
calculus, the urethra can be readily accessible at distal penile and
perineal locations. In male horses, a perineal urethrotomy can be conv
erted to a urethrostomy for permanent diversion of urine flow. Surgery
of the urethra in female horses is indicated less frequently than in
males. Primary lesions of the female urethra are rare, and surgical tr
eatment of this structure is most often associated with abnormalities
of the urinary tract. Manual and surgical dilation of the urethra in m
ares can facilitate the removal of urinary calculi. In some mares, a m
ucosal extension of the urethra is necessary to provide a more caudal
exit for urine and to reduce abnormal accumulation of urine in the vag
inal vestibule.