THE FIRST [4- FACILE SYNTHESIS OF AZEPINES(3] ANNULATION OF FISCHER CARBENE COMPLEXES WITH AZADIENES )

Authors
BARLUENGA J TOMAS M BALLESTEROS A SANTAMARIA J LOPEZORTIZ F
Citation
J. Barluenga et al., THE FIRST [4- FACILE SYNTHESIS OF AZEPINES(3] ANNULATION OF FISCHER CARBENE COMPLEXES WITH AZADIENES ), Journal of the Chemical Society, Chemical Communications, (3), 1994, pp. 321-322
Citations number
12
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
3
Year of publication
1994
Pages
321 - 322
Database
ISI
SICI code
0022-4936(1994):3<321:TF[FSO>2.0.ZU;2-#
Abstract
The reaction of 3-iminoprop-1-enylamines 1 with entacarbonyl(1-methoxy prop-2-enylidene)chromium(O) complexes leads stereoselectively to subs tituted 5H-6,7-dihydroazepines in high yields; the process takes place at low temperature and is thought to involve a tandem imine cycloprop anation-Cope rearrangement.