Sg. Lee et al., DRUG ERUPTION DUE TO BUFFERIN(R) SHOWING ERYTHEMA EXUDATIVUM MULTIFORME WITH A PHOTO-RECALL-LIKE PHENOMENON, EJD. European journal of dermatology, 8(4), 1998, pp. 280-282
A 21-year-old woman who had been taking several kinds of analgesics to
treat dysmenorrhea developed episodic attacks of a purpuric macular e
ruption and a burning sensation on unexposed areas of the upper chest
and back where she had sustained severe sunburn eight months earlier.
Targetlike lesions developed on these areas after intake of Bufferin(R
), a combination of aspirin and dialuminate. After the eruptions had a
bated following systemic administration of a corticosteroid agent, a c
hallenge test was performed, using a quarter of a tablet of Bufferin(R
). The patient developed a temporary burning sensation and a erythemat
ous color on the previously sunburned skin. We diagnosed this case as
a drug eruption due to Bufferin(R) showing erythema exsudativium multi
forme with a photo-recall-like phenomenon. In our case, skin tests wou
ld be useful to confirm the causal drug.