SYNTHESIS OF PROTECTED GUANIDINIUM LINKED DINUCLEOSIDE INCORPORABLE INTO AN OLIGONUCLEOTIDE USING SOLID-PHASE DNA METHODOLOGY

Authors
BARAWKAR DA LINKLETTER B BRUICE TC
Citation
Da. Barawkar et al., SYNTHESIS OF PROTECTED GUANIDINIUM LINKED DINUCLEOSIDE INCORPORABLE INTO AN OLIGONUCLEOTIDE USING SOLID-PHASE DNA METHODOLOGY, Bioorganic & medicinal chemistry letters, 8(12), 1998, pp. 1517-1520
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
8
Issue
12
Year of publication
1998
Pages
1517 - 1520
Database
ISI
SICI code
0960-894X(1998)8:12<1517:SOPGLD>2.0.ZU;2-V
Abstract
The synthesis of novel fully protected guanidinium linked dinucleoside for incorporation into oligonucleotide using solid-phase DNA synthesi s methodology was developed. The three different protecting groups sel ected allow different deprotection conditions. (C) 1998 Elsevier Scien ce Ltd. All rights reserved.