EFFECT OF GUARANA ON EXERCISE IN NORMAL AND EPINEPHRINE-INDUCED GLYCOGENOLYTIC MICE

The tonic action of water Guarana extract, (Paullinia cupana MART.), w as investigated in normal, exercised, and epinephrine-induced glycogen olytic mice. A water extract of Guarana(GW)(500 mg/kg) increased the b lood glucose level (p<0.001) and decreased the liver glycogen contents of mice 60 min after oral maltose administration (p<0.05). GW also si gnificantly suppressed exercise-induced hypoglycemia (60 min: p<0.05). However, GW did not affect the blood glucose in epinephrine-induced g lycogenolytic and exercise mice. These findings indicate that the supp ressive mechanism of hypoglycemia might he due to the promotion of gly cogen resolution.