EPOXIDE-TERTIARY AMINE COMBINATIONS AS EFFICIENT CATALYSTS FOR METHANOL CARBONYLATION INTO METHYL FORMATE IN THE PRESENCE OF CARBON-DIOXIDE

The influence of CO2 on the carbonylation of methanol into methyl form ate was investigated with two classes of catalytic systems: MeO- and e poxide-amine combinations. In the absence of CO2, NaOMe is the more ac tive, but its efficiency is rapidly destroyed by CO2. On the other han d, the epoxide-amine system is much less sensitive to the presence of CO2. Different classes of amines and epoxides have been tested. Tertia ry alkyl amines and terminal epoxides are the most efficient. Phosphin es associated with an epoxide have also been found to be able to catal yse this reaction. On the basis of P-31 NMR studies, a plausible mecha nism which can also be applied to amines is proposed for the reaction. (C) 1998 Elsevier Science B.V. All rights reserved.