P. Timmerman et al., NOVEL ROUTES FOR THE SYNTHESIS OF UPPER RIM AMINO AND METHOXYCARBONYLFUNCTIONALIZED CALIX[4]ARENES CARRYING OTHER TYPES OF FUNCTIONAL-GROUPS, Synthesis, (2), 1994, pp. 185-189
The selective functionalization of calix[4]arenes 1 by iodination at t
he upper rim in the presence of other functionalities is described. Th
e resulting (partly) iodinated calix[4]arenes 2 are good starting mate
rials for the preparation of both the corresponding carboxylic ester a
nd amino derivatives 3 and 6, respectively.