Hl. Casele et Sa. Laifer, FACTORS INFLUENCING PRECONCEPTION CONTROL OF GLYCEMIA IN DIABETIC WOMEN, Archives of internal medicine, 158(12), 1998, pp. 1321-1324
Background: Although periconceptional glycemic control directly impact
s perinatal outcome for pregestational diabetic women, these women sti
ll frequently enter pregnancy with suboptimal control of glycemia. Obj
ectives: To determine how frequently diabetic women enter pregnancy wi
th suboptimal glycemic control and to identify factors, associated wit
h not achieving optimal periconceptual control of glycemia. Patients a
nd methods: Pregestational diabetic women (n = 55) who attended the Ma
ternal Fetal Medicine Faculty Practice or the Resident Medical Complic
ations Obstetric Clinic, Magee Women's Hospital, Pittsburgh, Pa, were
administered a brief questionnaire pertaining to periconceptional educ
ation and control of glycemia. Levels of periconceptional hemoglobin A
(1c) were measured in all patients, Results: Sixty-one percent of preg
estational diabetic women presented for prenatal care with suboptimal
control of their blood glucose levels (hemoglobin A(1c) measurement, >
0.08). Of the 55 diabetic women who participated in the questionnaire,
47 (86%) were under the care of a physician for their diabetes, 45 (8
2%) monitored their glucose level at least 3 times per day, 34 (60%) s
tated that they had been advised to plan a pregnancy, and 29 (53%) sta
ted that they had planned their pregnancies. Women who had not been ad
vised to achieve target hemoglobin A(1c) levels were:more likely to en
ter pregnancy with suboptimal control of their blood glucose levels (P
=.02).Women who experienced prior complications with pregnancy were s
ignificantly more likely to enter pregnancy with suboptimal control of
their blood glucose levels (P=.02). Conclusions: Diabetic women frequ
ently enter pregnancy with suboptimal control of glycemia. Women not a
dvised to achieve target glucose or hemoglobin A(1c) levels were more
likely to enter pregnancy with suboptimal control of glycemia.