THE SCIENCE AND THERAPY OF GLUCOCORTICOID-INDUCED BONE LOSS

Authors
LANE NE LUKERT B
Citation
Ne. Lane et B. Lukert, THE SCIENCE AND THERAPY OF GLUCOCORTICOID-INDUCED BONE LOSS, Endocrinology and metabolism clinics of North America, 27(2), 1998, pp. 465
Citations number
112
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Endocrinology and metabolism clinics of North America → ACNP
ISSN journal
08898529
Volume
27
Issue
2
Year of publication
1998
Database
ISI
SICI code
0889-8529(1998)27:2<465:TSATOG>2.0.ZU;2-L
Abstract
Glucocorticoids are critical in the management of chronic, noninfectio us, inflammatory diseases. Bone loss is a II-cost devastating side eff ect of these powerful medications. Glucocorticoids produce bone loss b y altering calcium metabolism suppressing gonadal hormone production, and inhibiting bone formation. Now that the mechanism of glucocorticoi d-induced bone loss is understood and effective medications are availa ble, this disease can be prevented and reversed.