OBJECTIVE: to study the immediate and early postoperative results obta
ined in patients subjected to laparoscopic resection of colorectal can
cer. PATIENTS AND METHOD: a prospective, observational cohort study wa
s initiated in January 1993, involving 50 patients subjected to laparo
scopic resection for colorectal adenocarcinoma (rectal amputation in 1
0 cases, lower rectal resection in 13, recto-sigmoidectomy in 18, and
miscellaneous colectomies in 9 cases). Seventy-percent of the tumors w
ere in IUCC stages II and III. Mean follow-up was 21 months. RESULTS:
conversion to open surgery was required in 18 cases (36%), Intraoperat
ive problems were limited to a single urethral lesion, while postopera
tive complications were recorded in 11 patients (22%), and were manage
d conservatively: a urinary fistula secondary to the aforementioned ur
ethral lesion; subclinical dehiscence of the anastomosis (2 cases); ph
lebitis (1 case); infection of the surgical wound (4 cases), and urina
ry and pulmonary infection (1 case each). There were no differences be
tween converted surgery (i.e. conventional laparotomy) and those opera
tions completed endoscopically (with a final assisted or combined mini
laparotomy) in terms of the length of the surgical resection piece, th
e length of the distal margin of the specimen or the number of lymph n
odes. Global hospital stay ranged from 9-12 days, versus 5-7 in the gr
oup without complications. Global survival is 78% at 42 months, with a
disease-free interval of 53% at this time. CONCLUSIONS: laparoscopic
colorectal resection presents an incidence of intra- and postoperative
complications characteristic of major surgery, with no differences in
surgical specimen size with respect to those operations converted to
laparotomy. Global survival is similar to that reported in the literat
ure for open surgery.