Women enrolled in a multicenter prospective study were evaluated to id
entify any possible relationship between depressive symptoms and the u
se of contraceptive implants. Women choosing Norplant(R) implants (n =
910) were evaluated before starting this contraceptive and were reint
erviewed at 6 months and 2 years. Women who continued the method had l
ower depressive symptom scores before initiating Norplant implants tha
n did the women who discontinued the method or who were lost to follow
up. Among the continuing Norplant implant users, the mean scores were
similar before starting Norplant and at 6 months (7.9 vs 7. 7). The s
trongest overall predictor of the depressive symptom score was relatio
nship satisfaction. At 24 months, the subgroup of continuing users wit
h decreased relationship satisfaction had an increase in depressive sy
mptom score, but those with stable or improved relationships had stabl
e depressive symptom scores. The subjects with the highest (ie, worst)
scores at enrollment demonstrated improved scores during follow-up. T
hese results are reassuring for women who are concerned that Norplant
use may adversely affect their mood. CONTRACEPTION 1998;57:241-245 (C)
1998 Elsevier Science Inc. All rights reserved.