POSTOPERATIVE RADIOTHERAPY AND SURGERY IN STAGE-I ENDOMETRIAL CARCINOMA - A 10-YEAR EXPERIENCE

Background: Data from the literature show that the incidence of pelvic recurrences in poor prognosis endometrial carcinoma is significantly reduced by combined surgery and radiotherapy compared to surgery alone . Methods: In this paper we analyze the results of the combined treatm ent surgery plus adjuvant irradiation in patients with endometrial car cinoma with regard to survival, site of progression, and toxicity, The surgical treatment consisted of total abdominal hysterectomy and bila teral salpingo-oophorectomy. Pelvic and para-aortic node dissection wa s performed. Results: The overall 5-year survival was 88%, Three patie nts had local failure, Ten patients with local control of disease had distant metastases and 2 had local and distant recurrences. Conclusion s: Our experience confirms the data of the literature, Postoperative i rradiation is a safe and well tolerated treatment which can achieve go od local control in high-risk stage I endometrial carcinoma, The contr ol of distant metastases remains an open issue.