ADULT GRANULOSA-CELL TUMOR OF THE OVARY - A CLINICO PATHOLOGICAL-STUDY OF 35 CASES

Aims and background: Adult granulosa cell tumor has a low malignant po tential but requires an extensive follow-up of more than 5 years to ac curately assess tumor activity. The aim of the present study was to ev aluate the clinical characteristics, the treatment and the outcome of this rare ovarian tumor. Study design: A retrospective review of 35 ca ses treated at primary onset of disease during a 23-year period from 1 971 to 1993. Results: The disease-free survival rate for stages IA-B-C at 5 and 10 years was 90% and 84%, respectively; for stages Ill-IV th e 5-year freedom from progression rate was 16%. Conclusions: The most important prognostic factor appears to be the extent of tumor involvem ent outside of the ovary.