BALOS CONCENTRIC SCLEROSIS IN A 4-YEAR-OLD JAPANESE INFANT

We report the youngest known case with Balo's concentric sclerosis (Ba lo disease), a variant of multiple sclerosis. This 4-year-old Japanese boy was diagnosed by clinical manifestations and by characteristic fi ndings on magnetic resonance imaging (MRI). Dexamethasone was given in travenously, 3 mg twice daily for 10 days. The clinical manifestations were resolved within 2 weeks, and the MRI findings were markedly impr oved after 3 weeks. Following the initiation of steroid therapy, he sh owed remarkable clinical and physical improvement. It cannot be exclud ed that the clinical improvement resulted from the steroid therapy. (C ) 1998 Elsevier Science B.V. All rights reserved.