DIASTEREOSELECTIVE ANIONIC AND RADICAL CONJUGATE ADDITION ON A CHIRALENONE - A ROUTE TO MULTICHIRAL ARRAYS

1,4 Addition of several alkyl groups using cuprates and radicals on a conformationally biased chiral enone 3 derived from carbohydrate is de scribed, showing essentially identical diastereoselection in anionic a nd radical processes and dramatic influence of the alkyl group size on the sense of 1,2-asymmetric induction.