SYNTHESIS OF NEW 4-BENZOYL-5-HYDROXY-3-TRIFLUOROMETHYLPYRAZOLE DERIVATIVES VIA [1,3] REARRANGEMENTS OF BENZOYL GROUP USING TERT-BUTYLLITHIUM

Authors
JEON DJ YU DW YUN KY RYU EK
Citation
Dj. Jeon et al., SYNTHESIS OF NEW 4-BENZOYL-5-HYDROXY-3-TRIFLUOROMETHYLPYRAZOLE DERIVATIVES VIA [1,3] REARRANGEMENTS OF BENZOYL GROUP USING TERT-BUTYLLITHIUM, Synthetic communications, 28(12), 1998, pp. 2159-2166
Citations number
4
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
28
Issue
12
Year of publication
1998
Pages
2159 - 2166
Database
ISI
SICI code
0039-7911(1998)28:12<2159:SON4D>2.0.ZU;2-5
Abstract
The l-3-trifluoromethyl-5-p-toluenesulfonyloxypyrazole derivatives (7a - c) were synthesized by a new procedure involving rearrangement of t he benzoyl groups in 5-benzoyloxy-4-bromo-3-trifluoromethylpyrazole de rivatives (5a - c) to 4-benzoyl-5-hydroxy-3-trifluoromethylpyrazoles ( 6a - c) via lithium-bromide exchange using tert-butyllithium.