A CONCISE ENANTIOSPECIFIC SYNTHESIS OF NUPHAR PIPERIDINE ALKALOIDS - TOTAL SYNTHESIS OF (-)-ANHYDRONUPHARAMINE, (-)-NUPHARAMINE, (-)-NUPHENINE AND (-3-EPINUPHARAMINE())
T. Honda et al., A CONCISE ENANTIOSPECIFIC SYNTHESIS OF NUPHAR PIPERIDINE ALKALOIDS - TOTAL SYNTHESIS OF (-)-ANHYDRONUPHARAMINE, (-)-NUPHARAMINE, (-)-NUPHENINE AND (-3-EPINUPHARAMINE()), Journal of the Chemical Society, Chemical Communications, (4), 1994, pp. 499-500
Enantiospecific syntheses of (-)-anhydronupharamine, (-)-nupharamine,
(-)-nuphenine, and (+)-3-epinupharamine are achieved starting from (-)
- or (+)-carvone as chiral sources, in which a regioselective, reducti
ve fragmentation of the cyclopentane derivatives and an intramolecular
aza-Wittig reaction were involved as key reactions.