THE SHORT-TERM EFFECTS OF TOPICAL 1-PERCENT APRACLONIDINE ON MACULAR BLOOD-FLOW

Authors
GROSSMAN H BROWN GC CATER JR
Citation
H. Grossman et al., THE SHORT-TERM EFFECTS OF TOPICAL 1-PERCENT APRACLONIDINE ON MACULAR BLOOD-FLOW, Annals of ophthalmology. Glaucoma, 30(3), 1998, pp. 150-153
Citations number
19
Categorie Soggetti
Ophthalmology
Journal title
Annals of ophthalmology. Glaucoma
ISSN journal
10794794 → ACNP
Volume
30
Issue
3
Year of publication
1998
Pages
150 - 153
Database
ISI
SICI code
1079-4794(1998)30:3<150:TSEOT1>2.0.ZU;2-U
Abstract
The acute effects of topical 1% apraclonidine hydrochloride on retinal capillary blood flow in the macula were studied using the blue field entoptoscopic simulation technique. This was done immediately before i nstillation of one drop of 1% apraclonidine hydrochloride and at 60 mi nutes after instillation. We found a 17% increase in velocity of blood flow (P<0.01) and an 11% increase in the density of leukocytes within the macular capillaries (P<0.05) at I hour after instillation of the drug. There was no significant difference in pulsatility of blood flow .