E. Manfredi et al., A DYNAMIC DETERMINISTIC MODEL TO EVALUATE BREEDING STRATEGIES UNDER MIXED INHERITANCE, Genetics selection evolution, 30(2), 1998, pp. 127-148
A dynamic deterministic model is proposed to study the combined use of
an identified major gene and performance information for selection of
traits expressed in one sex. The model considers simultaneously combi
ned adult selection via within genotype thresholds, mating structures
according to major genotypes and preselection of young males. The appl
ication given indicates that an optimum combination between performanc
es and genotypic information yields better results, in terms of polyge
nic means, genotype frequencies and cumulated discounted genetic progr
ess, than classical selection ignoring the genotype information. The g
reatest advantage of combined selection occurs for rare recessive alle
les of large effect on phenotypes (up to +49 % for polygenic gains; +2
6 To for total genetic gain). Optimum within genotype proportions of s
elected individuals and mating structures vary with generations thus h
ighlighting the value of adynamic approach. (C) Inra/Elsevier, Paris.