B. Nuber et al., GYPSETIN, A NEW INHIBITOR OF ACYL-COA - CHOLESTEROL ACYLTRANSFERASE PRODUCED BY NANNIZZIA-GYPSEA VAR INCURVATA IFO-9228 .2. STRUCTURE DETERMINATION, Journal of antibiotics, 47(2), 1994, pp. 168-172
The elucidation of the structure of gypsetin, a new inhibitor of acyl-
CoA: cholesterol acyltransferase, is described in this paper. By spect
roscopic and X-ray crystallographic analyses, the structure of gypseti
n has been determined to be 8a, :1,5]azolidino[2,3-b]-[1]benzazolidine
-7,15-dione.