Functional magnetic resonance imaging (fMRI) is a method that combines
high anatomical spatial resolution with the ability to localise funct
ion. Visual and motor systems are among those that have received most
attention. Yet the clinical application is still limited. Recently, so
me investigators applied fmRI to study patients with multiple sclerosi
s. Patients with partial motor weakness disclosed a larger area of cor
tical activation bilaterally by contrast with healthy volunteers when
using the affected arm, whereas patients with optical neuritis disclos
ed a smaller area of activation, when stimulating the affected eye. Th
ese results show that different systems might react heterogeneously.