We calculate in a k-averaging approximation, the vertex corrections fo
r pairing at a Van Hove singularity mediated by an Einstein phonon. Th
e vertex correction leads to a modest reduction in T-c, which can stil
l reach the experimental values for realistic phonon couplings, and to
a significant deepening of the dip in the isotope shift at the T-c ma
ximum. Interference between first- and second-order vertex graphs dimi
nishes the effect of the Coulomb interaction on T-c. The isotope-shift
dip is shallower for repulsive Coulomb interaction, and deeper in the
case of an attractive interaction introduced to model an excitonic co
ntribution to pairing.