During a radiotherapy treatment, a dosimetric verification or a geomet
ric localization can be done, in order to assess the quality of the tr
eatment. The dosimetric verification is generally performed measuring
the dose at some points inside (natural cavities) or outside the patie
nt, and comparing it to the dose at the same points calculated and pre
dicted by the treatment planning system. This can be done either with
thermoluminescent or diodes dosimeters or with ionization chambers. Th
e geometric localization can be done acquiring a portal image of the p
atient. Portal imaging can be performed either with films placed betwe
en metallic screens, or with an electronic portal Imaging device such
as fluoroscopic systems, solid state devices or matrix ionization cham
ber systems. In order to assess possible field placement errors, the p
ortal images have to be compared with Images obtained with the simulat
or in the same geometric conditions and/or with the digitally reconstr
ucted radiograph (DRR) obtained with the treatment planning system. In
particular, when using matrix ionization chamber systems, the portal
images contain also information regarding the exit dose. This means th
at this kind of imaging device can be used both for geometric localiza
tion and for dosimetric verification. In this case, the exit dose meas
ured by the portal image can be compared with the exit dose calculated
and predicted by the treatment planning system, Some ''in-vivo'' appl
ications of this methodology are presented.