A MULTIPLE INTERVAL PHYSICAL MAP OF THE PERICENTROMERIC REGION OF HUMAN-CHROMOSOME-10

Five intervals in the pericentromeric region of human chromosome 10 ha ve been defined using a panel of somatic cell hybrids carrying portion s of the chromosome. The map positions of twelve markers, consisting o f four genes and eight anonymous DNA segments, have been localized by assignment to one of the five intervals. Several other markers could b e placed in specific intervals by genetic linkage to assigned loci. Wh en previously published data are incorporated, the summary map of the pericentromeric region encompasses thirty-two loci in bands 10p11.2-q1 1.2.