REDUCTION OF CYCLOSPORINE-INDUCED GINGIVAL OVERGROWTH FOLLOWING A CHANGE TO TACROLIMUS - A CASE-HISTORY INVOLVING A LIVER-TRANSPLANT PATIENT

DURING IMMUNOSUPPRESSION With cyclosporine, gingival overgrowth, a min or secondary effect, may appear in the first weeks of treatment. In ce rtain cases it may affect the function and/or esthetic appearance in a manner intolerable to the patient. A new immunnosuppressive molecule, tacrolimus, presently used as a treatment of second choice to control acute corticoresistant rejection, may bring oral comfort to these pat ients, since it reduces gingival overgrowth to negligible levels.