PREPARATIVE-SCALE CONVERSION OF D-XYLOSE INTO HYDROPHILICALLY FUNCTIONALIZED PYRAZOLES

Authors
DIEHL V CUNY E LICHTENTHALER FW
Citation
V. Diehl et al., PREPARATIVE-SCALE CONVERSION OF D-XYLOSE INTO HYDROPHILICALLY FUNCTIONALIZED PYRAZOLES, Heterocycles, 48(6), 1998, pp. 1193-1201
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
48
Issue
6
Year of publication
1998
Pages
1193 - 1201
Database
ISI
SICI code
0385-5414(1998)48:6<1193:PCODIH>2.0.ZU;2-E
Abstract
An expeditious, 4-step procedure is described for the conversion of bu lk-scale accessible D-xylose into 5-hydroxymethyl-1-phenylpyrazole-3-c arboxaldehyde (3), which, in turn, is converted into various pyrazole building blocks with versatile application profiles, such as the 1-phe nylpyrazole-3,5-dicarboxylic acid (9), the respective 3,5-dialdehyde ( 10), and 3,5-bis(aminomethyl)-1-phenylpyrazole (13).