The most severe form of kidney disease is renal failure, a life-threat
ening condition known as end-stage renal disease (ESRD). Though social
work intervention is an integral part of the response to serious kidn
ey disease, the topic has been noticeably absent in the discipline's l
iterature. This article synthesizes the research on the psyche-social
aspects of end-stage renal disease, with a particular focus on dialysi
s patients at different stages of the life cycle. Social work services
are particularly important to dialysis patients because (1) ESRD infl
uences patients' psyche-social environments and (2) the psyche-social
environments in which ESRD sufferers live impact the course of the dis
ease and physical well-being. Intervention issues are discussed. The r
eview found that most research on this topic lacks adequate sampling t
o generalize to the ESRD population. Future research needs to address
this shortcoming and increase sample sizes to allow for statistical co
ntrols.