BODY-MASS PREDICTS THE SURVIVAL OF PATIENTS WITH NEW INTERNATIONAL FEDERATION OF GYNECOLOGY AND OBSTETRICS STAGE IB1 AND IB2 CERVICAL-CARCINOMA TREATED WITH RADICAL HYSTERECTOMY

BACKGROUND. The authors evaluated the impact of body mass on survival and morbidity of patients with new International Federation of Gynecol ogy and Obstetrics (FIGO) Stage IB1 and IB2 cervical carcinoma managed with radical hysterectomy. METHODS. Two hundred twenty-nine patients with Stage IB1 or IB2 cervical carcinoma treated with radical hysterec tomy were studied in a multivariate logistic regression analysis. The body mass index (BMI) and the ponderal index (PI) were used as measure s of body mass and were analyzed as predictors of recurrence, survival , and complications in light of the new staging system. RESULTS. Twent y-seven of 229 patients died of recurrent disease. A low BMI or a high PI were predictive of poor survival Tumor greatest dimension, lymph n ode involvement, BMI, and PI were all independent predictors of surviv al (P = 0.0006). The only independent predictor of complications was p ara-aortic lymph node dissection (P = 0.0026). CONCLUSIONS. Cervical c arcinoma patients with a low body mass, as indicated by a low BMI or a high PI, were found to have poor survival after undergoing radical hy sterectomy. Additional predictors of poor survival included lymph node metastases and increased tumor size. BMI and PI are more important pr edictors of survival than the new FIGO Stages IB1 and IB2. Body mass i s not predictive of complications. (C) 1998 American Cancer Society.