PROGRESSION OF HYPERTROPHIC CARDIOMYOPATHY TO DILATED CARDIOMYOPATHY - A CASE-REPORTS AND REVIEW OF THE LITERATURES

Left ventricular systolic function in hypertrophic cardiomyopathy (HCM P) does not usually deteriorate even in the end stage of the disease. However, occasionally cases of HCMP progress to a similar farm of dila ted cardiomyopathy (DCMP) with a decreased systolic function and dilat ed left ventricle. We report two cases of HCMP which progressed to DCM P during follow-up. Our cases have been documented by serial M-mode ec hocardiography which shows a prominent decrease in the left ventricula r systolic function and a chamber enlargement of the left ventricle. T here are various explanations of the pathogenesis of the functional an d morphological myocardial deterioration of HCMP progressing to DCMP, and more cases should be studied to determine the pathogenesis and pre vention of this end-stage feature of HCMP.