H. Legarrec et al., ELECTROTHERMAL FACTORS OPTIMIZATION IN ELECTROTHERMAL ATOMIC-ABSORPTION SPECTROMETRY VIA AN OPTIMAL EXPERIMENTAL-DESIGN MATRIX, Analytica chimica acta, 368(1-2), 1998, pp. 59-70
A new approach is proposed to optimize some instrumental electrothermi
c parameters, i.e. injected volume, calcination duration, calcination
and atomization temperatures, gas flow, in electrothermal atomic absor
ption spectrometry. It is based on the monitoring of the detection lim
it estimation variation by using an unconventional experimental design
well adapted to a particular experimental domain. This method was tes
ted on Cd, Mn and Cu in sea water. By comparison with the default oper
ating conditions, the limits of detection were improved in some cases
and always obtained on carrying out less experiments than usual. (C) 1
998 Elsevier Science B.V.