TRANSCRIPTIONAL CONTROL - TAT COFACTORS AND TRANSCRIPTIONAL ELONGATION

Authors
YANKULOV K BENTLEY D
Citation
K. Yankulov et D. Bentley, TRANSCRIPTIONAL CONTROL - TAT COFACTORS AND TRANSCRIPTIONAL ELONGATION, Current biology, 8(13), 1998, pp. 447-449
Citations number
21
Categorie Soggetti
Biology,Biology
Journal title
Current biology → ACNP
ISSN journal
09609822
Volume
8
Issue
13
Year of publication
1998
Pages
447 - 449
Database
ISI
SICI code
0960-9822(1998)8:13<447:TC-TCA>2.0.ZU;2-D
Abstract
HIV-1 gene expression requires the transactivator Tat, which stimulate s viral transcript elongation. Recent results show that two cellular c yclin-dependent kinases, which phosphorylate the carboxy-terminal doma in of the RNA polymerase II large subunit, contact Tat and contribute to the control of transcriptional elongation. (C) Current Biology Ltd.