EREMOPHILANE SESQUITERPENES FROM CACALIA-ROBOROWSKII

Nine new eremophilane sesquiterpenes were isolated from the methanol e xtract of the roots of Cacalia roborowskii. They were identified as 8 beta, 10 beta-dihydroxy-6 beta-methoxyleremophilenolide 3 beta-acetoxy -8 beta,10 beta-dihydroxy-6 beta-methoxyeremophilenolide, 3 beta-aceto xyl-8 beta,10 beta-dihydroxy-6 beta-methoxyeremophilenolide, 3 beta-(2 -methylbutyryloxy)-8 beta,10 beta-dihydroxy-6 beta-methoxyeremophileno lide, and 8 beta-hydroxy-6 beta-methoxyeremophil-7(11),9-dien-8,12-oli de, 8-oxo-eremophila-6,9-dien-12-oic acid, 3 beta-acetoxyl-8-oxo-eremo phila-6,9-dien-12-oic acid, 3 beta-angeloxyl-8-oxo-eremphila-6,9-dien- 12-oic acid and;3 ethylbutyryloxyl)-8-oxo-eremophila-6,9-dien-12-oic a cid, respectively, based on ID and 2D NMR experiments. (C) 1998 Publis hed by Elsevier Science Ltd. All rights reserved.