BONE-MARROW TRANSPLANTATION AND GENE-THERAPY FOR LYSOSOMAL STORAGE DISEASES

Authors
HOOGERBRUGGE PM VALERIO D
Citation
Pm. Hoogerbrugge et D. Valerio, BONE-MARROW TRANSPLANTATION AND GENE-THERAPY FOR LYSOSOMAL STORAGE DISEASES, Bone marrow transplantation, 21, 1998, pp. 34-36
Citations number
20
Categorie Soggetti
Hematology,Oncology,Immunology,Transplantation
Journal title
Bone marrow transplantation → ACNP
ISSN journal
02683369
Volume
21
Year of publication
1998
Supplement
2
Pages
34 - 36
Database
ISI
SICI code
0268-3369(1998)21:<34:BTAGFL>2.0.ZU;2-6
Abstract
Allogeneic bone marrow transplantation with marrow from HLA-identical donors has been used with increasing frequency to treat patients with; lysosomal storage diseases. The effects of bone marrow transplantation largely depend on the type and stage of the disease, Generally, 'visc eral symptoms' can be largely improved by transplantation, but skeleta l lesions are relatively unaffected by transplantation. The effect on neurological symptoms varies.