C. Balzer et al., TRANSJUGULAR INTRAHEPATIC PORTOSYSTEMIC SHUNT FOR BLEEDING ANGIODYSPLASIA-LIKE LESIONS IN PORTAL-HYPERTENSIVE COLOPATHY, Gastroenterology, 115(1), 1998, pp. 167-172
Portal-hypertensive colopathy has attracted interest in recent years b
ecause such lesions can cause life-threatening hemorrhage. In contrast
to upper gastrointestinal bleeding from varices, there is no establis
hed therapy for bleeding from angiodysplasia-like lesions. This case r
eport describes the first successful use of transjugular intrahepatic
portosystemic shunt (TIPS) for long-term control of bleeding from angi
odysplasia-like colonic lesions in a patient with cirrhosis caused by
chronic hepatitis B infection. During an 18-month course after TIPS, a
ngiodysplasia-like lesions disappeared without any further evidence of
recurrent hematochezia, TIPS may be helpful as second-line treatment
in patients with recurrent portal-hypertensive bleeding from colonic a
ngiodysplasia-like lesions who do not tolerate or are unresponsive to
treatment with beta-adrenergic blockers.