THE BIOSYNTHESIS OF THE FUNGAL MEROTERPENOIDS BOVIQUINONE-3 AND BOVIQUINONE-4 FOLLOWS 2 DIFFERENT PATHWAYS

Authors
MUHLBAUER A BEYER J STEGLICH W
Citation
A. Muhlbauer et al., THE BIOSYNTHESIS OF THE FUNGAL MEROTERPENOIDS BOVIQUINONE-3 AND BOVIQUINONE-4 FOLLOWS 2 DIFFERENT PATHWAYS, Tetrahedron letters, 39(29), 1998, pp. 5167-5170
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
29
Year of publication
1998
Pages
5167 - 5170
Database
ISI
SICI code
0040-4039(1998)39:29<5167:TBOTFM>2.0.ZU;2-X
Abstract
A kev step in the biosynthesis of the fungal meroterpenoids boviquinon e-3 and -4 is the prenylation of 3,4-dihydroxybenzoic acid. In fruit-b odies of Suillus bovinus boviquinone-4 is formed by geranylgeranylatio n of 3,4-dihydroxybenzoic acid at C-5, whereas in Chroogomphus rutilus the farnesyl side chain of boviquinone-3 is introduced at C-2. The bi osynthesis of the terpenoid chain of boviquinone-4 follows the mevalon ate route. (C) 1998 Elsevier Science Ltd. All rights reserved.