EXTERNAL QUALITY ASSESSMENT OF MOLECULAR BIOLOGY-BASED METHODS USED IN LABORATORIES OF CLINICAL-CHEMISTRY AND HUMAN-GENETICS

The Reference Institute of Bioanalysis of the German Society of Clinic al Chemistry has performed the first external assessment of molecular genetics methods used in medical diagnosis. The following procedures w ere tested: (I) DNA preparation from whole blood, (II) PCR amplificati on using ''standard'' primers, and (III) submarine agarose gel electro phoresis. Out of 50 participants, 45 returned samples for evaluation.