ACUTE BUDD-CHIARI SYNDROME-ASSOCIATED WITH ACTIVATED PROTEIN-C RESISTANCE DURING INTRAVENOUS ANTICOAGULANT TREATMENT

The Budd-Chiari syndrome is a rare but serious condition defined as he patic venous outflow obstruction. This article presents a case of acut e Budd-Chiari syndrome in a 13-year-old woman with activated protein C resistance while she was bring treated with intravenous heparin infus ion for previously documented deep venous thrombosis. Activated protei n C resistance caused by factor V Leiden mutation has emerged as the m ost prevalent hereditary cause of venous thromboembolism and should be considered as an etiologic factor in patients with Budd-Chiari syndro me.