SYNTHESIS OF 4-SUBSTITUTED IMIDAZOLES VIA PALLADIUM-CATALYZED CROSS-COUPLING REACTIONS

Authors
JETTER MC REITZ AB
Citation
Mc. Jetter et Ab. Reitz, SYNTHESIS OF 4-SUBSTITUTED IMIDAZOLES VIA PALLADIUM-CATALYZED CROSS-COUPLING REACTIONS, Synthesis, (6), 1998, pp. 829-831
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
6
Year of publication
1998
Pages
829 - 831
Database
ISI
SICI code
0039-7881(1998):6<829:SO4IVP>2.0.ZU;2-Y
Abstract
Imidazoles bearing vinyl and aryl substitution in the 4-position can b e prepared using palladium-catalyzed cross-coupling reactions of 1-tri tylimidazol-4-yltin and -zinc reagents in 67-80% yield. Importantly, t hese coupling methods appear to be general for aryl and vinyl bromides , iodides, and triflates.