IMPLICATIONS OF HORMESIS FOR BIOMEDICAL AGING RESEARCH

Rather than being an exception, non-linearity between dose and respons e are the rule in biological systems. It might even be anticipated tha t at some doses a response opposite to that seen at high doses could b e elicited (hormesis). Such non-linearity with dose has multiple impli cations for numerous aspects of biomedical research on aging and for e xperimental design. Moreover, the implications of such non-linearity a re such that governmental regulatory activities and other areas of pub lic health administration will be affected to a large extent once horm esis is widely recognized, The implications with regard to environment al intervention and subsequent regulatory decisions will certainly pro foundly affect the political process, as well.